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Kindy, Mark
One or more keywords matched the following items that are connected to Kindy, Mark
Item TypeName
Academic Article Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.
Academic Article Expression of glutathione-S-transferase isozyme in the SY5Y neuroblastoma cell line increases resistance to oxidative stress.
Academic Article Abeta deposition is essential to AD neuropathology.
Academic Article Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3.
Academic Article Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
Academic Article Oxidized high-density lipoprotein induces neuron death.
Academic Article Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice.
Academic Article Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease.
Academic Article Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics.
Academic Article High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.
Academic Article Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner.
Academic Article Vitamin D3-enriched diet correlates with a decrease of amyloid plaques in the brain of A?PP transgenic mice.
Academic Article The cysteine protease inhibitor, E64d, reduces brain amyloid-? and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, ?-secretase activity.
Academic Article Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease.
Academic Article Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.
Academic Article RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.
Academic Article Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation.
Academic Article Neprilysin regulates amyloid Beta peptide levels.
Academic Article RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
Academic Article Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
Academic Article Neprilysin protects neurons against Abeta peptide toxicity.
Academic Article Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein.
Academic Article Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.
Academic Article Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.
Academic Article A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology.
Academic Article Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimer's disease.
Academic Article Transcranial laser therapy attenuates amyloid-? peptide neuropathology in amyloid-? protein precursor transgenic mice.
Academic Article Deletion of the cathepsin B gene improves memory deficits in a transgenic ALZHeimer's disease mouse model expressing A?PP containing the wild-type ?-secretase site sequence.
Concept Amyloid beta-Protein Precursor
Concept Amyloid beta-Peptides
Academic Article Brain pyroglutamate amyloid-? is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic.
Academic Article High-Sodium Diet Has Opposing Effects on?Mean Arterial Blood Pressure and?Cerebral Perfusion in a Transgenic Mouse Model of Alzheimer's Disease.
Academic Article GM6 Attenuates Alzheimer's Disease Pathology in APP Mice.
Academic Article Key signaling pathways regulate the biological activities and accumulation of amyloid-beta.
Academic Article Effects of GrandFusion Diet on Cognitive Impairment in Transgenic Mouse Model of Alzheimer's Disease.
Academic Article Control of ?-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-?/? and Nuclear Factor ?-B.
Academic Article cAMP-induced decrease in cell-surface laminin receptor and cellular prion protein attenuates amyloid-? uptake and amyloid-?-induced neuronal cell death.
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  • Amyloid beta Peptides